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  1. major depression

    • n.
      a mental condition characterized by a persistently depressed mood and long-term loss of pleasure or interest in life, often with other symptoms such as disturbed sleep, feelings of guilt or inadequacy, and suicidal thoughts.
    • noun: major depression, plural noun: major depressions

    • 更多解釋
    • n.
      a mental condition characterized by a persistently depressed mood and long-term loss of ...

    Oxford American Dictionary